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SD Locus (Shedding)

he SD Locus (SD) influences shedding levels in dogs through genetic variations in the MC5R and RSPO2 genes.

Affected Genes: MC5R

Inheritance: Complex Inheritance

References: Hayward JJ, Castelhano MG, Oliveira KC, Corey E, Balkman C, Baxter TL, Casal ML, Center SA, Fang M, Garrison SJ, Kalla SE, Korniliev P, Kotlikoff MI, Moise NS, Shannon LM, Simpson KW, Sutter NB, Todhunter RJ, Boyko AR. Complex disease and phenotype mapping in the domestic dog. Nat Commun 2016 Jan; 7:10460. [PubMed: 26795439]