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Myostatin Deficiency (Whippet and Longhaired Whippet Type)

Myostatin Deficiency in Whippets and Longhaired Whippets is a genetic condition that leads to pronounced muscular development and enhanced athletic performance due to a mutation affecting muscle growth regulation.

Affected Genes: MSTN

Inheritance: Autosomal Incomplete Dominant

Breed: Longhaired Whippet
Whippet

General Information:

How to Read Your Dog's Test Results for this Genetic Variant:

Two Variants Detected: Dog Likely Affected

One Variant Detected: Dog Possibly Affected

No Variants Detected: No Effect

Gene / Testing Information:

References: Mosher DS, Quignon P, Bustamante CD, Sutter NB, Mellersh CS, Parker HG, Ostrander EA. A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genet. 2007 May 25;3(5):e79. [PubMed: 17530926] Shelton GD, Engvall E. Gross muscle hypertrophy in whippet dogs is caused by a mutation in the myostatin gene. Neuromuscul Disord. 2007 Oct;17(9-10):721-2. [PubMed: 17651971]